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1

Understanding and Modulating Mammalian-Microbial Communication for Improved Human Health

Mani, Sridhar, Boelsterli, Urs A., Redinbo, Matthew R.

Journal:

Annual Review of Pharmacology

Year:

2014

Language:

english

File:

PDF, 1.52 MB

english, 2014

2

Plastocyanin: Structural and functional analysis

Matthew R. Redinbo, Todd O. Yeates, Sabeeha Merchant

Journal:

Journal of Bioenergetics and Biomembranes

Year:

1994

Language:

english

File:

PDF, 3.31 MB

english, 1994

3

REGULATION OF CYP3A GENE TRANSCRIPTION BY THE PREGNANE X RECEPTOR*

Goodwin, Bryan, Redinbo, Matthew R., Kliewer, Steven A.

Journal:

Annual Review of Pharmacology

Year:

2002

Language:

english

File:

PDF, 488 KB

english, 2002

4

The Microbiota, Chemical Symbiosis, and Human Disease

Redinbo, Matthew R.

Journal:

Journal of Molecular Biology

Year:

2014

Language:

english

File:

PDF, 562 KB

english, 2014

5

Glucuronides in the Gut: Sugar-Driven Symbioses Between Microbe and Host

Pellock, Samuel J., Redinbo, Matthew R.

Journal:

Journal of Biological Chemistry

Year:

2017

Language:

english

File:

PDF, 539 KB

english, 2017

6

A rapid method for positioning small flexible molecules, nucleic acids, and large protein fragments in experimental electron density maps

David J. Diller, Ehmke Pohl, Matthew R. Redinbo, Bianca T. Hovey, Wim G.J. Hol

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

1999

Language:

english

File:

PDF, 602 KB

english, 1999

7

A database method for automated map interpretation in protein crystallography

David J. Diller, Matthew R. Redinbo, Ehmke Pohl, Wim G.J. Hol

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

1999

Language:

english

File:

PDF, 880 KB

english, 1999

8

Immobilization of active human carboxylesterase 1 in biomimetic silica nanoparticles

Jonathan S. Edwards, Amar Kumbhar, Adam Roberts, Andrew C. Hemmert, Carol C. Edwards, Philip M. Potter, Matthew R. Redinbo

Journal:

Biotechnology Progress

Year:

2011

Language:

english

File:

PDF, 496 KB

english, 2011

9

Crystal structure of the PXR–T1317 complex provides a scaffold to examine the potential for receptor antagonism

Yu Xue, Esther Chao, William J. Zuercher, Timothy M. Willson, Jon L. Collins, Matthew R. Redinbo

Journal:

Bioorganic & Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 1.24 MB

english, 2007

10

Crystal Structure of Human Carboxylesterase 1 Complexed with the Alzheimer's Drug Tacrine: from Binding Promiscuity to Selective Inhibition

Sompop Bencharit, Christopher L Morton, Janice L Hyatt, Peter Kuhn, Mary K Danks, Philip M Potter, Matthew R Redinbo

Journal:

Chemistry & Biology

Year:

2003

Language:

english

File:

PDF, 472 KB

english, 2003

11

Crystallization and preliminary structural analysis of Bacillus subtilis adenylosuccinate lyase, an enzyme implicated in infantile autism

Matthew R. Redinbo, Sithumini M. Eide, Randy L. Stone, Jack E. Dixon, Todd O. Yeates

Journal:

Protein Science

Year:

1996

Language:

english

File:

PDF, 1.31 MB

english, 1996

12

Activation of the human nuclear xenobiotic receptor PXR by the reverse transcriptase-targeted anti-HIV drug PNU-142721

Yuan Cheng, Matthew R. Redinbo

Journal:

Protein Science

Year:

2011

Language:

english

File:

PDF, 485 KB

english, 2011

13

Elucidating the ‘Jekyll and Hyde’ Nature of PXR: The Case for Discovering Antagonists or Allosteric Antagonists

Arunima Biswas, Sridhar Mani, Matthew R. Redinbo, Matthew D. Krasowski, Hao Li, Sean Ekins

Journal:

Pharmaceutical Research

Year:

2009

Language:

english

File:

PDF, 234 KB

english, 2009

14

Structural insights into CPT-11 activation by mammalian carboxylesterases

Bencharit, Sompop, Morton, Christopher L., Howard-Williams, Escher L., Danks, Mary K., Potter, Philip M., Redinbo, Matthew R.

Journal:

Natural Structural Biology

Year:

2002

Language:

english

File:

PDF, 2.88 MB

english, 2002

15

Structural basis of heroin and cocaine metabolism by a promiscuous human drug-processing enzyme

Bencharit, Sompop, Morton, Christopher L., Xue, Yu, Potter, Philip M., Redinbo, Matthew R.

Journal:

Natural Structural Biology

Year:

2003

Language:

english

File:

PDF, 800 KB

english, 2003

16

Tyrosine partners coordinate DNA nicking by the Salmonella typhimurium plasmid pCU1 relaxase enzyme

Rebekah P. Nash, Franklin C. Niblock, Matthew R. Redinbo

Journal:

Year:

2011

Language:

english

File:

PDF, 606 KB

english, 2011

17

Orphan nuclear receptors adopted by crystallography

Holly A Ingraham, Matthew R Redinbo

Journal:

Current Opinion in Structural Biology

Year:

2005

Language:

english

File:

PDF, 530 KB

english, 2005

18

Structural insights into the function of type IB topoisomerases

Matthew R Redinbo, James J Champoux, Wim GJ Hol

Journal:

Current Opinion in Structural Biology

Year:

1999

Language:

english

File:

PDF, 526 KB

english, 1999

19

Promiscuity: what protects us, perplexes us

Matthew R Redinbo

Journal:

Drug Discovery Today

Year:

2004

Language:

english

File:

PDF, 59 KB

english, 2004

20

Keynote review: Mammalian carboxylesterases: From drug targets to protein therapeutics

Matthew R. Redinbo, Philip M. Potter

Journal:

Drug Discovery Today

Year:

2005

Language:

english

File:

PDF, 499 KB

english, 2005

21

Structural Flexibility in Human Topoisomerase I Revealed in Multiple Non-isomorphous Crystal Structures

Matthew R. Redinbo, Lance Stewart, James J. Champoux, Wim G.J. Hol

Journal:

Journal of Molecular Biology

Year:

1999

Language:

english

File:

PDF, 594 KB

english, 1999

22

Investigating the impact of bisphosphonates and structurally related compounds on bacteria containing conjugative plasmids

Rebekah P. Nash, Dan E. McNamara, W. Keith Ballentine III, Steven W. Matson, Matthew R. Redinbo

Journal:

Biochemical and Biophysical Research Communications

Year:

2012

Language:

english

File:

PDF, 1.47 MB

english, 2012

23

Mechanisms of Camptothecin Resistance by Human Topoisomerase I Mutations

Jill E Chrencik, Bart L Staker, Alex B Burgin, Philippe Pourquier, Yves Pommier, Lance Stewart, Matthew R Redinbo

Journal:

Journal of Molecular Biology

Year:

2004

Language:

english

File:

PDF, 2.12 MB

english, 2004

24

Crystal Structure of the Human LRH-1 DBD–DNA Complex Reveals Ftz-F1 Domain Positioning is Required for Receptor Activity

Isaac H. Solomon, Janet M. Hager, Rachid Safi, Donald P. McDonnell, Matthew R. Redinbo, Eric A. Ortlund

Journal:

Journal of Molecular Biology

Year:

2005

Language:

english

File:

PDF, 820 KB

english, 2005

25

Multisite Promiscuity in the Processing of Endogenous Substrates by Human Carboxylesterase 1

Sompop Bencharit, Carol C. Edwards, Christopher L. Morton, Escher L. Howard-Williams, Peter Kuhn, Philip M. Potter, Matthew R. Redinbo

Journal:

Journal of Molecular Biology

Year:

2006

Language:

english

File:

PDF, 943 KB

english, 2006

26

Crystal Structure of the Cofactor-Binding Domain of the Human Phase II Drug-Metabolism Enzyme UDP-Glucuronosyltransferase 2B7

Michael J. Miley, Agnieszka K. Zielinska, Jeffrey E. Keenan, Stacie M. Bratton, Anna Radominska-Pandya, Matthew R. Redinbo

Journal:

Journal of Molecular Biology

Year:

2007

Language:

english

File:

PDF, 1.02 MB

english, 2007

27

A Novel Fold in the TraI Relaxase–Helicase C-Terminal Domain Is Essential for Conjugative DNA Transfer

Laura M. Guogas, Sarah A. Kennedy, Jin-Hyup Lee, Matthew R. Redinbo

Journal:

Journal of Molecular Biology

Year:

2009

Language:

english

File:

PDF, 1.06 MB

english, 2009

28

Crystal Structure of the HEAT Domain from the Pre-mRNA Processing Factor Symplekin

Sarah A. Kennedy, Monica L. Frazier, Mindy Steiniger, Ann M. Mast, William F. Marzluff, Matthew R. Redinbo

Journal:

Journal of Molecular Biology

Year:

2009

Language:

english

File:

PDF, 2.68 MB

english, 2009

29

Crystal Structure of the Plant Epigenetic Protein Arginine Methyltransferase 10

Yuan Cheng, Monica Frazier, Falong Lu, Xiaofeng Cao, Matthew R. Redinbo

Journal:

Journal of Molecular Biology

Year:

2011

Language:

english

File:

PDF, 2.84 MB

english, 2011

30

Functional Anatomy of Phospholipid Binding and Regulation of Phosphoinositide Homeostasis by Proteins of the Sec14 Superfamily

Gabriel Schaaf, Eric A. Ortlund, Kimberly R. Tyeryar, Carl J. Mousley, Kristina E. Ile, Teresa A. Garrett, Jihui Ren, Melissa J. Woolls, Christian R.H. Raetz, Matthew R. Redinbo, Vytas A. Bankaitis

Journal:

Year:

2008

Language:

english

File:

PDF, 2.66 MB

english, 2008

31

Coactivator Binding Promotes the Specific Interaction Between Ligand and the Pregnane X Receptor

Ryan E. Watkins, Paula R. Davis-Searles, Mill H. Lambert, Matthew R. Redinbo

Journal:

Journal of Molecular Biology

Year:

2003

Language:

english

File:

PDF, 1.88 MB

english, 2003

32

The 1.5-.ANG. crystal structure of plastocyanin from the green alga Chlamydomonas reinhardtii

Redinbo, Matthew R., Cascio, Duilio, Choukair, Marie K., Rice, Danny, Merchant, Sabeeha, Yeates, Todd O.

Journal:

Year:

1993

Language:

english

File:

PDF, 3.16 MB

english, 1993

33

2.1 Å Crystal Structure of Human PXR in Complex with the St. John's Wort Compound Hyperforin †,‡

Watkins, Ryan E., Maglich, Jodi M., Moore, Linda B., Wisely, G. Bruce, Noble, Schroeder M., Davis-Searles, Paula R., Lambert, Mill H., Kliewer, Steven A., Redinbo, Matthew R.

Journal:

Year:

2003

Language:

english

File:

PDF, 428 KB

english, 2003

34

The crystal structure of human UDP-glucuronosyltransferase 2B7 C-terminal end is the first mammalian UGT target to be revealed: the significance for human UGTs from both the 1A and 2B families

Radominska-Pandya, Anna, Bratton, Stacie M., Redinbo, Matthew R., Miley, Michael J.

Journal:

Drug Metabolism Reviews

Year:

2010

Language:

english

File:

PDF, 1.56 MB

english, 2010

35

Xenobiotic-sensing nuclear receptors involved in drug metabolism: a structural perspective

Wallace, Bret D., Redinbo, Matthew R.

Journal:

Drug Metabolism Reviews

Year:

2013

Language:

english

File:

PDF, 1.94 MB

english, 2013

36

Rifampicin-Independent Interactions between the Pregnane X Receptor Ligand Binding Domain and Peptide Fragments of Coactivator and Corepressor Proteins

Navaratnarajah, Punya, Steele, Bridgett L., Redinbo, Matthew R., Thompson, Nancy L.

Journal:

Year:

2012

Language:

english

File:

PDF, 685 KB

english, 2012

37

PXR antagonists and implication in drug metabolism

Mani, Sridhar, Dou, Wei, Redinbo, Matthew R.

Journal:

Drug Metabolism Reviews

Year:

2013

Language:

english

File:

PDF, 1.55 MB

english, 2013

38

Rifampicin - Independent Interactions Between the Pregnane X Receptor Ligand Binding Domain and Peptide Fragments of Co-Activator and Co-Repressor Proteins

Navaratnarajah, Punya, Steele, Bridgett L., Redinbo, Matthew R., Thompson, Nancy L.

Journal:

Biophysical Journal

Year:

2012

Language:

english

File:

PDF, 91 KB

english, 2012

39

Molecular Modeling of CPT-11 Metabolism by Carboxylesterases (CEs): Use of pnb CE as a Model †

Wierdl, Monika, Morton, Christopher L., Nguyen, Nathan K., Redinbo, Matthew R., Potter, Philip M.

Journal:

Year:

2004

Language:

english

File:

PDF, 301 KB

english, 2004

40

Structural and Functional Analysis of the Human Nuclear Xenobiotic Receptor PXR in Complex with RXRα

Wallace, Bret D., Betts, Laurie, Talmage, Garrick, Pollet, Rebecca M., Holman, Natalie S., Redinbo, Matthew R.

Journal:

Journal of Molecular Biology

Year:

2013

Language:

english

File:

PDF, 2.69 MB

english, 2013

41

Characterization of the N -Acetyl-α- d -glucosaminyl l -Malate Synthase and Deacetylase Functions for Bacillithiol Biosynthesis in Bacillus anthracis ,

Parsonage, Derek, Newton, Gerald L., Holder, Robert C., Wallace, Bret D., Paige, Carleitta, Hamilton, Chris J., Dos Santos, Patricia C., Redinbo, Matthew R., Reid, Sean D., Claiborne, Al

Journal:

Year:

2010

Language:

english

File:

PDF, 8.42 MB

english, 2010

42

The human microbiome is a source of therapeutic drug targets

Wallace, Bret D, Redinbo, Matthew R

Journal:

Current Opinion in Chemical Biology

Year:

2013

Language:

english

File:

PDF, 674 KB

english, 2013

43

Stereoselective Hydrolysis of Pyrethroid-like Fluorescent Substrates by Human and Other Mammalian Liver Carboxylesterases

Huang, Huazhang, Fleming, Christopher D., Nishi, Kosuke, Redinbo, Matthew R., Hammock, Bruce D.

Journal:

Chemical Research in Toxicology

Year:

2005

Language:

english

File:

PDF, 322 KB

english, 2005

44

Bacterial β-glucuronidase inhibition protects mice against enteropathy induced by indomethacin, ketoprofen or diclofenac: mode of action and pharmacokinetics

Saitta, Kyle S., Zhang, Carmen, Lee, Kang Kwang, Fujimoto, Kazunori, Redinbo, Matthew R., Boelsterli, Urs A.

Journal:

Year:

2014

Language:

english

File:

PDF, 366 KB

english, 2014

45

Mammalian short palate lung and nasal epithelial clone 1 (SPLUNC1) in pH-dependent airway hydration

Tarran, Robert, Redinbo, Matthew R.

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2014

Language:

english

File:

PDF, 1.19 MB

english, 2014

46

Nuclear Receptor (PXR), Ligand and Co-Activator Interactions Measured by Total Internal Reflection Fluorescence Microscopy

Navaratnarajah, Punya, Steele, Bridgett L., Redinbo, Matthew R., Thompson, Nancy L.

Journal:

Biophysical Journal

Year:

2011

Language:

english

File:

PDF, 69 KB

english, 2011

47

Mo2014 A Small Molecule Inhibitor of Intestinal Bacterial β-Glucuronidase Prevents Ketoprofen-Induced Small Intestinal Ulceration in Mice

Saitta, Kyle S., Zhang, Carmen, Redinbo, Matthew R., Boelsterli, Urs A.

Journal:

Gastroenterology

Year:

2013

Language:

english

File:

PDF, 58 KB

english, 2013

48

Symbiotic Bacterial Metabolites Regulate Gastrointestinal Barrier Function via the Xenobiotic Sensor PXR and Toll-like Receptor 4

Venkatesh, Madhukumar, Mukherjee, Subhajit, Wang, Hongwei, Li, Hao, Sun, Katherine, Benechet, Alexandre P., Qiu, Zhijuan, Maher, Leigh, Redinbo, Matthew R., Phillips, Robert S., Fleet, James C., Korta

Journal:

Year:

2014

Language:

english

File:

PDF, 4.80 MB

english, 2014

49

Electrostatic Contribution of Serine Phosphorylation to the Drosophila SLBP−Histone mRNA Complex †

Thapar, Roopa, Marzluff, William F., Redinbo, Matthew R.

Journal:

Year:

2004

Language:

english

File:

PDF, 375 KB

english, 2004

50

Crystal Structures of Human Carboxylesterase 1 in Covalent Complexes with the Chemical Warfare Agents Soman and Tabun †,‡

Fleming, Christopher D., Edwards, Carol C., Kirby, Stephen D., Maxwell, Donald M., Potter, Philip M., Cerasoli, Douglas M., Redinbo, Matthew R.

Journal:

Year:

2007

Language:

english

File:

PDF, 643 KB

english, 2007